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血管性血友病因子(von Willebrand Factor, vWF),是由第12號(hào)染色體的短臂所編碼的糖蛋白。vWF可同時(shí)與膠原纖維和血小板結(jié)合，當(dāng)血管破裂時(shí)大量血小板以vWF為中介，粘附在膠原纖維上，形成血栓，得以止血。在正常的生理?xiàng)l件下,絕大部份由內(nèi)皮細(xì)胞合成,其余則由巨噬細(xì)胞生成。前者產(chǎn)生后多儲(chǔ)存在W-P小體（Weibel-Palade body，WPB）內(nèi), 后者則儲(chǔ)存在血小板的顆粒中。它與一系列心血管疾病如動(dòng)脈粥樣硬化、急性冠狀動(dòng)脈綜合征、心房顫動(dòng)等均關(guān)系密切，vWF是一種重要的血漿成分。vWF在止血過程中主要由兩種作用：①與血小板膜GPⅠb-Ⅸ復(fù)合物及內(nèi)皮下膠原結(jié)合，介導(dǎo)血小板在血管損傷部位的黏附；②與因子Ⅷ結(jié)合，作為載體具有穩(wěn)定因子Ⅷ的作用。此外，vWF也能結(jié)合GPⅡb-Ⅲa，參與血小板的聚集過程。正常人血漿vWF濃度約為10mg/L。在內(nèi)皮細(xì)胞受刺激或損傷以及集體處于應(yīng)激狀態(tài)時(shí)，血漿vWF水平升高。vWF及某些止血與纖溶成分都是血栓性疾病的獨(dú)立危險(xiǎn)因素。相反，當(dāng)vWF基因發(fā)生缺失、插入點(diǎn)突變、剪切點(diǎn)替換或提前形成轉(zhuǎn)錄終止信號(hào)時(shí)，導(dǎo)致血漿vWF量有顯著減低或有質(zhì)的缺陷，不能完成其正常的止血功能時(shí)，即為vWD。
von Willebrand Factor (vWF)相關(guān)對(duì)照?
| 貨號(hào) | 品名 | 包裝 | 價(jià)格 | 品牌 |
| 5450312 | Technozym vWF:CBA Control Set 2x0,5 ml | CE | 2650.98 | Technoclone |
| 5450212 | Technozym vWF:Ag Control Set 2x0,5 ml | CE | 2650.98 | Technoclone |
| CEV20302 | Human vWF ELISA Kit Low (Negative) Reference Control | 1100 | AssayPro | |
| CEV20301 | Human vWF ELISA Kit High (Positive) Reference Control | 900 | AssayPro
|
von Willebrand Factor (vWF)抗體?
| 貨號(hào) | 品名 | 包裝 | 價(jià)格 | 品牌 |
| SARTW-IG | Sheep anti rat vWF - von Willebrand Factor purified IgG | 5 mg | 2975 | affinitybiologicals |
| SARTW-HRP | Sheep anti rat vWF - von Willebrand Factor peroxidase conjugated IgG | 0.2 mg | 3519 | affinitybiologicals |
| SACWF-IG | Sheep anti canine vWF - von Willebrand Factor purified IgG | 5 mg | 2839 | affinitybiologicals |
| SACWF-HRP | Sheep anti canine vWF - von Willebrand Factor peroxidase conjugated IgG | 0.2 mg | 3349 | affinitybiologicals |
| GAVWF-IG | Goat anti human vWF - von Willebrand Factor purified IgG | 2.5 mg | 2091 | affinitybiologicals |
| GAVWF-HRP | Goat anti human vWF - von Willebrand Factor peroxidase conjugated IgG | 0.15 mg | 3519 | affinitybiologicals |
| GAVWF-APFTC | Goat anti human vWF - von Willebrand Factor affinity purified, FITC conjugated IgG | 0.1 mg | 3519 | affinitybiologicals |
| GAVWF-APBIO | Goat anti human vWF - von Willebrand Factor affinity purified, Biotinylated IgG | 0.1 mg | 3519 | affinitybiologicals |
| GAVWF-AP | Goat anti human vWF - von Willebrand Factor affinity purified IgG | 0.5 mg | 4794 | affinitybiologicals |
| PAHVWF-S | Sheep anti-Human vWF | 1x1 mg | 1310.4 | Haematologic Technologies |
| PAHVWF-S | Sheep anti-Human vWF | 1x5 mg | 4499.04 | Haematologic Technologies |
| ADGESvWF8 | murine Mab against human vWF | 500 µg | 5575 | American Diagnostica Inc |
| SARTW-IG | Anti-Rat von Willebrand Factor (RvWF)sheep, purified IgG, | 5 mg | 2975 | Enzyme Research2016 |
| SARTW-HRP | Anti-Rat von Willebrand Factor (RvWF)sheep, perox-conj. IgG, | 0.2 mg | 3519 | Enzyme Research2016 |
| GAVWF-HRP | Anti-human von Willebrand Factor (vWF)goat, perox-conj. IgG, | 0.15 mg | 3519 | Enzyme Research2016 |
| GAVWF-APFTC | Anti-human von Willebrand Factor (vWF)goat, AP-FITC | 0.1 mg | 3519 | Enzyme Research2016 |
| GAVWF-AP | Anti-human von Willebrand Factor (vWF)goat, affinity purified IgG, | 0.5 mg | 4794 | Enzyme Research2016 |
| GAVWF-IG | Anti-human von Willebrand Factor (vWF)goat, affinity adsorbed IgG, | 2.5 mg | 2600 | Enzyme Research2016 |
| SACWF-IG | Anti-Canine von Willebrand Factor (CvWF)sheep, purified IgG, | 5 mg | 2839 | Enzyme Research2016 |
| SACWF-HRP | Anti-Canine von Willebrand Factor (CvWF)sheep, perox-conj. IgG, | 0.2 mg | 3349 | Enzyme Research2016 |
von Willebrand Factor (vWF)
| 貨號(hào) | 品名 | 包裝 | 價(jià)格 | 品牌 |
| PV10212 | Von Willebrand factor (vWF), Human | 100 ug | 4900 | AssayPro |
| ADG206 | Von Willebrand factor deficient human plasma | 1 mL | 2100 | American Diagnostica Inc |
| 2042 | von Willebrand Factor (vWF), human, fVIII free, frozen solution, dry-ice shipment | 100 µg | 9444 | American Diagnostica Inc |
| HCVWF-0190 | Human von Willebrand Factor | 1x100 µg | 4700.37204 | Haematologic Technologies |
| HCVWF-0190 | Human von Willebrand Factor | 5x100 µg | 21257.964 | Haematologic Technologies |
| HCVWF-0190 | Human von Willebrand Factor | 5x1 mg | 188487.2808 | Haematologic Technologies |
| HCVWF-0190 | Human von Willebrand Factor | 10x1 mg | 371305.7712 | Haematologic Technologies |
| HCVWF-0190 | Human von Willebrand Factor | 50x1 mg | 1669931.172 | Haematologic Technologies |
| HCVWF-0190 | Human von Willebrand Factor | 100x1 mg | 3264278.472 | Haematologic Technologies |
| HCVWF-0190 | Human von Willebrand Factor | 500x1 mg | 14703425.1 | Haematologic Technologies |
| HCVWF-0191 | Human von Willebrand Factor (Factor VIII free) | 1x100 µg | 5621.55048 | Haematologic Technologies |
| HCVWF-0191 | Human von Willebrand Factor (Factor VIII free) | 5x100 µg | 25391.457 | Haematologic Technologies |
| HCVWF-0191 | Human von Willebrand Factor (Factor VIII free) | 5x1 mg | 226043.0172 | Haematologic Technologies |
| HCVWF-0191 | Human von Willebrand Factor (Factor VIII free) | 10x1 mg | 445472.4456 | Haematologic Technologies |
| HCVWF-0191 | Human von Willebrand Factor (Factor VIII free) | 50x1 mg | 2004153.606 | Haematologic Technologies |
| HCVWF-0191 | Human von Willebrand Factor (Factor VIII free) | 100x1 mg | 3918551.364 | Haematologic Technologies |
| HCVWF-0191 | Human von Willebrand Factor (Factor VIII free) | 500x1 mg | 17644110.12 | Haematologic Technologies |
von Willebrand Factor (vWF)缺乏血漿
| 貨號(hào) | 品名 | 包裝 | 價(jià)格 | 品牌 |
| DP150K | vWF Deficient Plasma | 6 x 1 mL | 2220 | hyphen biomed |
| D203003 | Human vWF deficient plasma (Sodium Citrate) | 10 x 10 ml | 16000 | AssayPro |
| D203002 | Human vWF deficient plasma (Sodium Citrate) | 10 ml | 1800 | AssayPro |
| D203001 | Human vWF deficient plasma (Sodium Citrate) | 1 ml | 200 | AssayPro |
| D203012 | Human vWF deficient plasma (Serum) | 10 x 10 ml | 16000 | AssayPro |
| D203011 | Human vWF deficient plasma (Serum) | 10 ml | 1800 | AssayPro |
| D203010 | Human vWF deficient plasma (Serum) | 1 ml | 200 | AssayPro |
| D203009 | Human vWF deficient plasma (Heparin) | 10 x 10 ml | 16000 | AssayPro |
| D203008 | Human vWF deficient plasma (Heparin) | 10 ml | 1800 | AssayPro |
| D203007 | Human vWF deficient plasma (Heparin) | 1 ml | 200 | AssayPro |
| D203006 | Human vWF deficient plasma (EDTA) | 10 x 10 ml | 16000 | AssayPro |
| D203005 | Human vWF deficient plasma (EDTA) | 10 ml | 1800 | AssayPro |
| D203004 | Human vWF deficient plasma (EDTA) | 1 ml | 200 | AssayPro |
| VWF-DP | human von Willebrand Factor deficient plasma | 1ml | 163 | affinitybiologicals |
| VWF-LDP | human von Willebrand Factor deficient plasma | 1ml | 183 | affinitybiologicals |
von Willebrand Factor (vWF)?試劑盒
| 貨號(hào) | 品名 | 包裝 | 價(jià)格 | 品牌 |
| RK038A | ZYMUTEST vWF:CBA | Kit of 96 tests | 5370 | hyphen biomed |
| RK030A | ZYMUTEST vWF | Kit of 96 tests | 5790 | hyphen biomed |
| von Willebrand Factor | von Willebrand Factor elisa kit | 5 plate | 7633 | Enzyme Research2016 |
| 5450321 | Technozym vWF:CBA ELISA Typ VI 96 T. | RUO | 10603.92 | Technoclone |
| 5450311 | Technozym vWF:CBA ELISA Typ I 96 T. | CE | 7906.02 | Technoclone |
| 5450301 | Technozym vWF:CBA ELISA 96 T. | CE | 7788.72 | Technoclone |
| 5450310 | Technozym vWF:CBA Calibration Set 5x0,5 ml | CE | 2791.74 | Technoclone |
| 5450201 | Technozym vWF:Ag ELISA 96 T. | CE | 7788.72 | Technoclone |
| 5450210 | Technozym vWF:Ag Calibration Set 5x0,5 ml | CE | 2791.74 | Technoclone |
| ADG886 | IMUCLONE™ von Willebrand Factor-CB activity ELISA | 96 microwell plate | 10250 | American Diagnostica Inc |
| 828 | IMUBIND® vWF ELISA | 96 microwell plate | 8184 | American Diagnostica Inc |
| 885 | IMUBIND® vWF Activity ELISA | 96 microwell plate | 9756 | American Diagnostica Inc |
| EV2030-7 | Human Von Willebrand Factor (VWF) ELISA Kit (WHO Standard calibrated controls included) | 96 well plate | 5600 | AssayPro |
| EV2030-1 | Human Von Willebrand Factor (VWF) ELISA Kit | 96 well plate | 4760 | AssayPro |
| VWF-EIA | von Willebrand Factor | 5 plates | 7633 | affinitybiologicals |
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